The 2025 Welch Conference is an in-person and live-streamed event.
8:30 AM
Introductory Remarks
Frederick W. Brazelton, Chair of the Welch Foundation Board of Directors
Schedule 2025
Monday, October 27, 2025
Introductory Remarks & Conference Introduction
Profile
8:35 AM
Conference Introduction
Kevan M. Shokat, University of California, San Francisco Conference Chair
Session I - Drugs as Rescue Agents
8:40 AM
Alex Johnson
Brandeis University
Session Leader
8:50 AM
Pharmacological Adaptation of Proteostasis to Ameliorate Aging-associated Degenerative Diseases
Jeff Kelly, The Scripps Research Institute
9:35 AM
How Small Molecules Rescue a Folding Disease: Principles Learned From the Ion Channel CFTR
Jue Chen, Rockefeller University
10:35 AM
Antisense Oligonucleotides for Rare-Disease Therapy
Adrian Krainer, Cold Spring Harbor Labs
Session II - Living Therapeutics
12:30 PM
Emily Dykhuizen
Purdue University
Session Leader
1:25 PM
TBD
Wendell Lim, University of California, San Francisco
Keynote Speaker
2:30 PM
Towards a Pan-Sarbecovirus Vaccine to Protect Against SARS-CoV-2 Variants and Animal Sarbecoviruses Without Updating
Pamela Bjorkman, California Institute of Technology
Tuesday, October 28, 2025
Session III - Chemoproteomics & Drug Discovery
8:30 AM
Devin Schweppe
University of Washington
Session Leader
8:40 AM
Activity-Based Proteomics – Protein and Ligand Discovery on a Global Scale
Ben Cravatt, The Scripps Research Institute
9:25 AM
Reversible Covalent Inhibitors: From Serendipity to Clinical Trials
Jack Taunton, University of California, San Francisco
10:25 AM
Chemical Proteomic Strategies to Investigate Reactive Cysteines
Franthie Weerapana, Boston College
2025 Welch Awardee Lecture
11:10 AM
TBD
TBD
Session IV - Molecular Glues
1:15 PM
An Heeseon
Memorial Sloan Kettering Cancer Center
Session Leader
1:25 PM
The Rise of Molecular Glues and Proximity-Inducing Compounds
Stuart Schreiber, Harvard University
2:10 PM
Co-opting the Ubiquitin System for Therapeutic Benefit
Ingrid Wertz, Lyterian Therapeutics
3:10 PM
Rewiring Transcription Using Chemically Induced Proximity
Nathanael Gray, Stanford University
3:55 PM
Closing
Kevan M. Shokat, University of California, San Francisco, Conference Chair